Aripiprazole Lauroxil,an Alkermes novel Drug has been submitted for NDA (New Drug Application) approval from US FDA for use in treatment of Schizophrenia.Aripiprazole Lauroxil is an injectablee drug with one-month & two -month formulations as an anti-psychotic for treatment of Schizophrenia.Aripiprazole lauroxil gets converted to Aripiprazole once administered in to the body,which is a long acting drug based on a unique , Akemers Propietary LinkeRX technology .
The positive results from pivotal phase 3 clinical study assessing the efficacy and safety studies in which this novel drug showed significant improvement of schizophrenia compared to placebo.
Chemistry of Aripiprazole Lauroxil
Molecular Formula : C36H51Cl2N3O4
Molecular Weight :660.71
IUPAC name:[7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-2-oxo-3,4-dihydroquinolin-1-yl]methyl dodecanoate
Chemical Structure:
The positive results from pivotal phase 3 clinical study assessing the efficacy and safety studies in which this novel drug showed significant improvement of schizophrenia compared to placebo.
Chemistry of Aripiprazole Lauroxil
Molecular Formula : C36H51Cl2N3O4
Molecular Weight :660.71
IUPAC name:[7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-2-oxo-3,4-dihydroquinolin-1-yl]methyl dodecanoate
Chemical Structure: