GAL-021, an investigational agent of Galleon pharmaceuticals has been shown to reverse opioid induced respiratory depression while maintaining pain relief in clinical trials .
Opiod Drugs like Methadone,Fentanyl which are commonly used to manage Pre-operative and Post -operative (surgery) Pain are associated with increased risk of adverse effects like respiratory depression.To treat this Drugs like Naloxone are prescribed ,but they counteract Analgesic effect of opiods which is the worst case of pain .Where as , GAL-021 witout effecting Analgesic activity prevents respiratory depression while uisng opiods.
This study is published in a recent Anesthiology issue .
Opiod Drugs like Methadone,Fentanyl which are commonly used to manage Pre-operative and Post -operative (surgery) Pain are associated with increased risk of adverse effects like respiratory depression.To treat this Drugs like Naloxone are prescribed ,but they counteract Analgesic effect of opiods which is the worst case of pain .Where as , GAL-021 witout effecting Analgesic activity prevents respiratory depression while uisng opiods.
This study is published in a recent Anesthiology issue .