Showing posts with label astham. Show all posts
Showing posts with label astham. Show all posts

Arnuity Ellipta approved for used in Asthma treatment

Arnuity Ellipta of GlaxoSmithkline has been approved by US FDA for maintenance treatment  of Asthma as prophylactic therapy in 12 years or older patients.
Arunity Ellipta (fluticasone furoate ) is an inhalation powder which is a once -daily inhaled corticosteroid medicine with doses of 100 mcg and 200 mcg. 
However,it is not indicated for relief of acute bronchospasm.

GAL-021 , a novel agent reverses respiratory depression while maintaining pain relief in opioid use

GAL-021, an investigational agent of Galleon pharmaceuticals has been shown to reverse opioid induced respiratory depression while maintaining pain relief in clinical trials .
Opiod Drugs like Methadone,Fentanyl  which are commonly used to manage Pre-operative and Post -operative (surgery) Pain are associated with increased risk of adverse effects like respiratory depression.To treat this Drugs like Naloxone are prescribed ,but they counteract Analgesic effect of opiods which is the worst case of pain .Where as , GAL-021  witout effecting Analgesic activity  prevents respiratory depression while uisng opiods. 
This study is published in a  recent Anesthiology issue .