Showing posts with label eap. Show all posts
Showing posts with label eap. Show all posts

Palbociclib Expanded Access Program (EAP) in US

Palbociclib Expanded access program(EAP) is initiated by Pfizer in USA for investigational CDK 4/6 inhibitor.With this programme Palbociclib in combination with letorozole is made available for women withHR+( Hormone receptor positive), and HER2-(Human epidermal growth facotr receptor 2 negative) advanced breast CANCER for whom this letrozole is considered as appropiate therapy/treatment.
Pabociclib when administered orally,it selective inhibits CDK's 4 and 6 (cyclin dependent kinase)to regain cell cycle control and will block further cell proliferation.